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SOHO 2022 | Preliminary data from the MANIFEST study: pelabresib in combination with ruxolitinib in MF

Prithviraj Bose, MBBS, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses preliminary findings from the MANIFEST study (NCT02158858), which is evaluating the safety and efficacy of pelabresib in combination with ruxolitinib in patients with myelofibrosis (MF). Dr Bose comments on the encouraging results observed in arms two and three of this study, including the reduction in spleen volume in patients, as well as the improvement in bone marrow fibrosis.This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.

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