In this video, Raajit Rampal, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, briefly discusses the growing role of genomic testing in myeloproliferative neoplasms (MPNs), and further emphasizes how genomic testing has influenced risk stratification, treatment, and clinical trial design in the field. This interview took place at the third annual Texas MPN Workshop (TMW) 2022, held in San Antonio, TX.