The risk of skeletal adverse events with zoledronic acid

Heinz Ludwig

Heinz Ludwig, MD, from the Wilhelminen Cancer Research Institute, Vienna, Austria, discusses two promising studies presented at the 2017 World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France. The first investigated the combination of zoledronic acid and denusomab (NCT01345019). The results found that zoledronic acid reduced the risk of skeletal related adverse events, however there was a decreased risk of progression. The second study, the Cardamom trial (NCT02315716) investigated the combination of carfilzomib, cyclophosphamide, and dexamethasone. Dr Ludwig states that although not every trial shows successful results, they do offer new information.

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