Nataliya Buxbaum, MD, Roswell Park Comprehensive Cancer Center, Buffalo, NY, comments on the importance of personalizing treatment for chronic graft-versus-host disease (cGvHD). In the past five years, three drugs have been approved by the FDA for GvHD. However, it is still necessary to determine which drug is best for each patient. This interview took place at the Transplantation & Cellular Therapy (TCT) Meetings of ASTCT™ and CIBMTR® 2022 in Salt Lake City, Utah.