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SOHO 2023 | Insights into the biology of pediatric MDS

Robert Hasserjian, MD, Massachusetts General Hospital, Boston, MA, provides a comparison between myelodysplastic syndromes (MDS) in the pediatric and adult settings. Dr Hasserjian talks on distinctions in genetic background, with germline predispositions identified in a larger proportion of pediatric patients. Dr Hasserjian also comments on differences in the International Consensus Classification (ICC) of MDS, explaining that the MDS/acute myeloid leukemia (AML) entity does not apply to pediatric patients due to the comparatively slower progression of MDS to AML in this population. This interview took place at the Eleventh Annual Meeting of the Society of Hematologic Oncology (SOHO 2023) held in Houston, TX.

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