Sergio Giralt, MD, Memorial Sloan-Kettering Cancer Center, New York, NY, discusses some of the highlights in multiple myeloma presented at ASH 2020. The impact of measurable residual disease (MRD) on patient outcomes is discussed, as well as the importance of using MRD as a way of evaluating treatments in the future. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.