Kathryn Tringale, MD, Memorial Sloan Kettering Cancer Center, New York City, NY, discusses a study which analyzed patterns of disease failure in a large cohort of patients with primary CNS lymphoma. Nearly all patients received methotrexate-based induction therapy, and 385 patients in this cohort received consolidation therapy. Results demonstrated that patients who experienced early relapse were more likely to fail at the original site of disease, whereas those who underwent consolidation therapy had unpredictable and distant relapses, suggesting a potential role for local treatment in this high-risk subgroup of patients. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.
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