Jose F. Camargo, MD, University of Miami, Miller School of Medicine, Miami, FL, provides an update in emergent topics in infectious disease and vaccines in patients undergoing hematopoietic cell transplantation and treatment with cellular therapies, including outcomes of transplant patients with COVID-19, as well as the role of the microbiome on the outcomes of patients undergoing transplant. This interview took place during the Transplantation & Cellular Therapy (TCT) 2021 Meetings.