Clark DuMontier, MD, MPH, VA Boston Healthcare System, Brigham and Women’s Hospital/Harvard Medical School, Boston, MA, discusses a real-world retrospective study comparing the less intense treatment regimen lenalidomide-dexamethasone (Rd) to the more intense triplet bortezomib-lenalidomide-dexamethasone (VRd) in elderly, frail patients with newly diagnosed multiple myeloma (NDMM). The findings confirm the benefit of VRd over Rd in moderate-severely frail patients, challenging the conventional view that frail patients should receive less intense treatment regimens. This interview took place at the 20th International Myeloma Society (IMS) Annual Meeting, held in Athens, Greece.
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