Tarek H Mouhieddine, MD, Dana-Farber Cancer Institute, Boston, MA, discusses how multiple myeloma patients with clonal hematopoeisis of undetermined potential (CHIP) are at an increased risk of cardiovascular disease and additional hematological malignancies. Dr Mouhieddine goes on to explain how immunomodulatory maintenance negates the negative effects of CHIP. This interview was recorded at the International Myeloma Workshop (IMW) 2019, held in Boston, MA.