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ASH 2023 | Responses in R/R MM treated with teclistamab following prior BCMA-directed therapy

Ariel Grajales-Cruz, MD, Moffitt Cancer Center, Tampa, FL, discusses the safety and efficacy of teclistamab in patients with relapsed/refractory (R/R) multiple myeloma (MM) who were previously treated with a B-cell maturation antigen (BCMA)-targeted therapy. A recent single-center study aimed to address disease outcomes in these patients, as BCMA pre-treated patients were excluded from the analysis of the MajesTEC-1 trial of teclistamab (NCT04557098), leading to a lack of data regarding outcomes in this group. Encouragingly, the outcomes in this patient population were comparable to those seen in MajesTEC-1. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Speakers Bureau: Amgen, Sanofi
Board of Directors/Advisory Committee: Sanofi, Cellectar, Janssen