Jan Philipp Bewersdorf, MD, Memorial Sloan Kettering Cancer Center, New York City, NY, shares the findings of a Phase Ib study evaluating the histone deacetylase (HDACi) entinostat in combination with pembrolizumab in patients with relapsed/refractory (R/R) myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML; NCT02936752). Overall, the trial reported limited efficacy for this novel treatment combination. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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