Jesús San Miguel, MD, PhD, University of Navarra Clinic, Pamplona, Spain, talks on the importance of having access to optimal tools, such as measurable residual disease (MRD) and imaging, for the diagnosis and monitoring of patients multiple myeloma, and the benefits of administering the best possible treatments in the frontline setting. This interview took place during the 18th International Myeloma Workshop (IMW 2021) congress.