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CAR-T Meeting 2024 | An update on the GoCART initiative: GoCART passports & new edition of the EBMT-EHA CAR-T handbook

In this video, Jürgen Kuball, MD, PhD, Utrecht University, Utrecht, Netherlands, provides an update on the EBMT-EHA GoCART initiative. This includes the new edition of the EBMT-EHA CAR-T handbook and the introduction of a GoCART passport, which allows healthcare professionals (HCPs) to demonstrate proficiency in CAR T-cell therapy. Dr Kuball highlights the importance of fostering connections between professionals involved in the coalition, which was made possible at the EBMT-EHA 6th European CAR T-cell Meeting in Valencia, Spain, where this interview took place.

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Transcript (edited for clarity)

The GoCART Coalition initiative is now in its fourth year and is really gaining speed. We launched, this year, two major initiatives.

The one initiative is the GoCART passport, which is sort of a driver’s license for physicians, not only physicians but also many other healthcare professionals, to be able to, in the future, show proficiency in CAR T-cell therapy...

The GoCART Coalition initiative is now in its fourth year and is really gaining speed. We launched, this year, two major initiatives.

The one initiative is the GoCART passport, which is sort of a driver’s license for physicians, not only physicians but also many other healthcare professionals, to be able to, in the future, show proficiency in CAR T-cell therapy. We collected many different stakeholders from different countries. If your country has not so far been approached, please approach us because we would like to include you in this initiative. And this initiative is also linked to the new edition of the EBMT handbook and EHA handbook for CAR-T.

So this meeting is, as always, amazing and the most amazing highlight for me is always meeting a lot of good old friends and meeting a lot of new friends. So while we set up this initiative of the GoCART coalition, we really went into different nations, nations I haven’t been in contact with so far before. This was, for me, the most important highlight, because I think we have forgotten in the last years, because of all the Teams meetings we have, that personal contact is the most important one for making connections.

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Disclosures

Patents: 
Exclusively licensed to Gadeta.
• WO2013147606 COMBINATORIAL GAMMA 9 DELTA 2 T CELL RECEPTOR CHAIN EXCHANGE
• WO2017212074 NOVEL METHOD FOR IDENTIFYING DELTAT-CELL (OR GAMMAT-CELL) RECEPTOR CHAINS OR PARTS THEREOF THAT MEDIATE AN ANTI-TUMOUR OR AN ANTI-INFECTIVE RESPONSE
• WO2017212072 HUMAN LEUKOCYTE ANTIGEN RESTRICTED GAMMA DELTA T CELL RECEPTORS AND METHODS OF USE THEREOF
• WO2018211115 COMPOSITIONS AND METHODS FOR CELL TARGETING THERAPIES

Exclusively licensed to Miltenyi Biotec:
• WO2016079333 USE OF ANTIBODIES FOR ENRICHMENT OF ENGINEERED T CELLS WITH EXOGENOUS IMMUNE RECEPTORS AND ANTIBODIES FOR USE IN DEPLETION OF ENGINEERED T CELLS

Joint patent UMCU with Miltenyi Biotec on “Novel CAR Concepts”:
• WO2020201527 MODIFIED IMMUNE RECEPTOR CONSTRUCTS