Kevin Kuo, MD, MSc, FRCPC, University Health Network, Toronto, Canada, discusses data collected in the BEYOND study (NCT03342404) evaluating the long-term effect of luspatercept plus best supportive care versus placebo plus best supportive care on non-transfusion dependent beta-thalassemia (NTDT)-related symptoms over 96 weeks. In an analysis of patient-reported outcomes (PRO) data, patients on luspatercept experienced durable symptom improvement over time, whereas those on the placebo exhibited a decrease in PRO scores. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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