In this study, Malin Hultcrantz, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, highlights a study which investigated the free light chain criteria used in the 2014 IMWG diagnostic criteria, and implications of this study in the future treatment of multiple myeloma. This interview took place at the European Hematology Association (EHA) Congress 2022 held in Vienna, Austria.