Jürgen Kuball, MD, PhD, Utrecht University, Utrecht, Netherlands, summarizes the key points from a discussion on allogeneic vs autologous chimeric antigen receptor T-cells (CAR-Ts) that took place at this year’s EBMT-EHA CAR T-cell Meeting. Whilst today, it is not feasible to produce and use allogeneic CAR-Ts in a clinical setting, it is expected that they will have a significant role in the future of CAR-T therapy. The role of academia within that field, however, remains unclear. According to Prof. Kuball, academia should play a role in both creating innovations in CAR-T therapy and supporting niche indications. This interview took place at the EBMT-EHA 4th European CAR T-cell Meeting which was held virtually in 2022.