Sham Mailankody, MBBS, Memorial Sloan Kettering Cancer Center, New York City, NY, discusses MRD assessment in multiple myeloma (MM). Specifically, Dr Mailankody outlines bone marrow MRD testing, assessed by next-generation flow-cytometry and alternative methods of disease evaluation in serum, such as mass spectrometry. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).