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SOHO 2024 | PROTACs as an emerging new drug class to treat hematologic malignancies

John Seymour, MBBS, FRACP, PhD, Peter MacCallum Cancer Centre, Melbourne, Australia, discusses proteolysis targeting chimeras (PROTACs) as an emerging drug class for treating hematologic malignancies. This drug class includes BTK degraders, which have shown effective degradation of BTK and high response rates in Phase I trials. This interview took place at the Twelfth Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) congress in Houston, TX.

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