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ASH 2022 | The need for disease-modifying therapies in MPNs

Andrew Kuykendall, MD, Moffitt Cancer Center, Tampa, FL, discusses the need for disease-modifying therapies in myeloproliferative neoplasms (MPNs), acknowledging that few drugs are able to induce complete remission (CR) in patients. Dr Kuykendall highlights the need for mutation-specific inhibitors of JAK2, as well as earlier clinical intervention in myelofibrosis (MF). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Protagonist: Other: Research Support; Imago Biosciences: Consultancy, Honoraria, Speakers Bureau; Incyte: Consultancy, Honoraria, Speakers Bureau; Blueprint Medicines Corporation: Consultancy, Honoraria, Research Funding, Speakers Bureau; Novartis: Consultancy, Honoraria, Speakers Bureau; Abbvie: Consultancy, Honoraria, Speakers Bureau; GSK – Sierra Oncology: Consultancy, Honoraria, Other: Research Support, Speakers Bureau; Prelude Pharmaceuticals: Other: Research Support; BMS: Consultancy, Honoraria, Other: Research Support, Speakers Bureau; Morphosys: Other: Research Support; Pharmaessentia: Consultancy, Honoraria, Speakers Bureau; CTI Biopharma: Consultancy, Honoraria, Speakers Bureau.