Joshua Richter, MD, Mount Sinai Medical Center, New York, NY, outlines the changing treatment landscape for patients with relapsed/refractory multiple myeloma including the approval of belantamab mafodotin, a BCMA targeting antibody-drug conjugate, as well as melflufen, evaluated in the HORIZON (NCT02963493) and OCEAN (NCT03151811) trials. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).