Ghayas Issa, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, shares some insights into two studies evaluating the use of the menin inhibitor revumenib for the treatment of patients with acute myeloid leukemia (AML). Dr Issa begins by summarizing the AUGMENT-101 study (NCT04065399), which assessed the optimal dosage of revumenib in patients with KMT2A-rearranged or NPM1-mutant AML, and demonstrated that patients treated with this agent achieved durable responses. Following this, Dr Issa highlights the findings of a follow-up study that investigated the role of revumenib in patients following hematopoietic stem cell transplant (HSCT). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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