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ASH 2023 | Phase I trial of copanlisib + nivolumab in patients with Richter’s transformation or transformed FL

In this video, Geoffrey Shouse, DO, PhD, City of Hope, Duarte, CA, gives an overview of a Phase I trial evaluating the safety and efficacy of copanlisib in combination with nivolumab in patients with transformed follicular lymphoma (FL) and Richter’s transformation (RT; NCT03884998). A small subset of patients with RT responded to this combination, and in patients with transformed FL, a promising response rate was observed, although the duration of response (DoR) was shorter. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Speakers Bureau: Beigene, Inc., Kite Pharmaceuticals
Consultancy: Kite Pharmaceuticals