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ASH 2022 | ASH highlights: results of the TRIANGLE study in MCL

Umberto Vitolo, MD, Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy, comments on recent developments in non-Hodgkin lymphoma (NHL) presented at ASH 2022, highlighting the TRIANGLE study (NCT02858258), which assessed ibrutinib combined with standard chemoimmunotherapy or as a substitute for autologous stem cell transplantation (ASCT) in younger patients with mantle cell lymphoma (MCL). The trial reported superior progression-free-survival (PFS) in groups treated with ibrutinib. Prof. Vitolo suggests that this is likely to have a significant impact on clinical practice. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Seagen, Genmab, Incyte, Costellation, Bayer, Regeneron: Consultancy; AbbVie, Incyte, Janssen, Gilead Sciences: Speakers Bureau.