iwCLL 2023 | BRUIN CLL-322: pirtobrutinib plus VR vs VR alone in R/R CLL
Jennifer Woyach, MD, Ohio State University College of Medicine, Columbus, OH, comments on BRUIN CLL-322 (NCT04965493), a Phase III open-label, randomized study comparing fixed duration pirtobrutinib plus venetoclax and rituximab (VR) with a standard regimen of VR in previously treated patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study aims to determine whether pirtobrutinib will provide additional efficacy when administered alongside the standard of care regimen for relapsed/refractory (R/R) CLL. This interview took place at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
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