Jonathon B. Cohen, MD, MS, of Winship Cancer Institute of Emory University, Atlanta, GA, outlines the next questions in mantle cell lymphoma, including a greater understanding of the requirement of frontline therapies, the management of disease using minimal residual measurements, as well as identifying patients appropriate for CAR T-cell therapies. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).