The relationship between mutations and precursor states in myelodysplastic syndromes (MDS) is a growing area of research, and advances in next-generation sequencing (NGS) have allowed experts to gain a better understanding of pre-MDS states. Early detection of precursor conditions, including clonal cytopenia of undetermined significance (CCUS) and clonal hematopoiesis of indeterminate potential (CHIP), can aid in the diagnosis and management of disease.

In this podcast, you will hear from experts Mrinal Patnaik, MBBS, Mayo Clinic, Rochester, MN, Zhuoer Xie, MD, MSCR, Moffitt Cancer Center, Tampa, FL, and Eric Padron, MD, Moffitt Cancer Center, Tampa, FL, who discuss clonal hematopoiesis and the impact of mutations in MDS, as well as the importance of better understanding precursor states. This discussion took place at the 1st International Workshop on Myelodysplastic Syndromes (iwMDS) held in Miami, FL.