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ERIC 2020

The European Research Initiative on CLL (ERIC) 2020 Virtual Meeting, New Frontiers in CLL Research, was held on 1-3 October 2020 and highlighted recent updates in the rational use of biomarkers, patient stratification, novel therapeutic targets, and appropriate patient management.

Leading experts in the field discussed the latest in CLL research, from basic to translational and clinical.

The full series of presentations can be viewed on-demand below.

With thanks to European Research Initiative on CLL and Open Audience for kind permission to VJHemOnc to share the proceedings online.

Day One

Day one of the meeting featured sessions on the genesis of CLL and disease trajectories.

Session I: The genesis of CLL
  • Exploring the roads to CLL; Freda Stevenson
  • MBL: Always a one-way ticket to CLL?; Lydia Scarfo
Session I
Session II: Disease trajectories: Outcomes, possible explanations and clinical implications
  • Spontaneous regression; Tatjana Stankovic
  • Clonal evolution: How is it reflected at the genome?; Catherine J. Wu
Session II

Day Two

Day two of the meeting featured sessions on resistance to apoptosis and proliferation.

Session III: Resistance to apoptosis
  • The anti-apoptotic phenotype: Cell-extrinsic drivers; Dimitar Efremov
Session III
Session IV: Proliferation: What lies beneath and how to target it?
  • CLL and microenvironmental addictions; Adrian Wiestner
  • Relevant bystander cells; Martina Seiffert
  • Targeting CLL cell proliferation: Clinical overview; Jan Burger
Session IV

Day Three

Day three of the meeting featured a session on networking and collaboration, frontline treatment and management of relapsed/refractory disease.

Session V: Networking and collaboration: Why and how
  • CLL within HARMONY; Francesc Bosch
Session V
Roundtable discussion: Frontline treatment: State-of-the-art
  • Chairs: Michael Hallek, John Seymour
  • Discussants: Florence Cymbalista, Matthew Davids, Kirsten Fischer, George Follows, Alessandra Tedeschi, William Wierda, Jennifer Woyach
Roundtable discussion I
Roundtable discussion: Management of relapsed/refractory disease: State-of-the-art
  • Chairs: Jennifer Brown, Peter Hillmen
  • Discussants: Antonio Cuneo, Barbara Eichhorst, Arnon Kater, Stephen Schuster, Michel van Gelder
Roundtable discussion II

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