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iwHRMM 2026 | Insights into fragmentomic and genomic profiling of cfDNA to track tumor burden in multiple myeloma

Dory Abelman, PhD, Dana-Farber Cancer Institute, Boston, MA, discusses his presentation on fragmentomic and genomic profiling of cell-free DNA (cfDNA) to track tumor burden in multiple myeloma. Dr Abelman notes that his team’s study found that peripheral blood cfDNA can recover a significant proportion of bone marrow-derived lesions, and that certain features of cfDNA may inform risk of early progression. This discussion took place at the 3rd International Workshop on High-Risk Multiple Myeloma (iwHRMM 2026), held in Charleston, SC.

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