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How AI can improve prognostication and transplant decisions in MDS

Matteo Della Porta, MD, IRCCS Humanitas Research Hospital, Milan, Italy, discusses the potential of artificial intelligence (AI) to improve prognostication and clinical decision-making in myelodysplastic syndromes (MDS). Prof. Della Porta highlights AI-based clinical decision support systems for optimizing transplantation timing, alongside emerging models that incorporate clonal evolution and longitudinal molecular data to refine risk stratification. This presentation took place at the 4th International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS/iwMPN) 2026, held in Washington, DC.

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