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IMS 2026 | Insights into a MAIC comparing IberDd against daratumumab plus IMiD containing regimens in myeloma

Sagar Lonial, MD, Winship Cancer Institute of Emory University, Atlanta, GA, discusses the results of a matching-adjusted indirect comparison (MAIC) analysis comparing iberdomide in combination with daratumumab and dexamethasone (IberDd) to daratumumab and IMiD-containing regimens in multiple myeloma, highlighting that iberdomide demonstrates a significantly higher measurable residual disease (MRD) negativity rate and a favorable safety profile, despite the comparisons not being head-to-head. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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