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SOHO 2026 | Key considerations for optimizing treatment sequencing in DLBCL

Gilles Salles, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, shares his insights on how to optimally sequence treatment for diffuse large B-cell lymphoma (R/R DLBCL), emphasizing that it is curable for most patients when the right regimen is used. Dr Salles highlights the importance of swiftly moving to second-line approaches, such as CAR T-cell therapy upon failure of first-line regimens, and notes that bispecific antibodies offer efficient treatment options, particularly in combination with gemcitabine and oxaliplatin (GemOx). This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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