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SOHO 2026 | Optimizing glofitamab use in R/R LBCL: insights into dosing and patient selection

Gilles Salles, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the efficacy of glofitamab in relapsed/relapsed large B-cell lymphoma (R/R LBCL), noting durable complete responses with minimal relapse after two to three years of follow-up. He discusses the step-up dosing schedule, which currently requires hospitalization due to the risk of CRS, as well as combination approaches and the ongoing challenge of optimizing patient selection. This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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