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SOHO 2026 | Evolving frontline strategies to reduce relapse in DLBCL

Stephen Ansell, MD, PhD, Mayo Clinic, Rochester, MN, discusses evolving approaches to reducing relapse in diffuse large B-cell lymphoma (DLBCL). He highlights how frontline choices such as polatuzumab vedotin plus R-CHP (Pola-R-CHP) and tafasitamab-based combinations can influence subsequent treatment options, while emerging bispecific and combination approaches may further improve outcomes. This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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