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EHA 2026 | Evolving treatment strategies and unmet needs in acute lymphoblastic leukemia

Marlise Luskin, MD, MSCE, Dana-Farber Cancer Institute, Boston, MA, discusses how the treatment landscape for acute lymphoblastic leukemia (ALL) is rapidly evolving with the integration of novel targeted therapies, including bispecific antibodies, antibody-drug conjugates, and CAR T-cell therapies. Dr Luskin explores how frontline strategies for both Philadelphia chromosome-positive and -negative ALL are expected to shift toward less intensive chemotherapy and more personalized approaches, while also highlighting the ongoing unmet need for effective therapies in T-cell ALL. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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