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ESH CLL 2026 | Fixed-duration acalabrutinib combinations in CLL

Gianluca Gaidano, MD, PhD, University of Eastern Piedmont, Vercelli, Italy, discusses emerging fixed-duration regimens combining acalabrutinib and venetoclax for chronic lymphocytic leukemia (CLL). He highlights how these strategies challenge the paradigm of indefinite BTK inhibitor therapy while maintaining efficacy and improving tolerability. This interview took place at the ESH CLL 2026 congress in Stockholm, Sweden.

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