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IMS 2024 | MILESTONE trial results: MRD response-adapted deferral of autoSCT in newly diagnosed myeloma

Susan Bal, MD, University of Alabama at Birmingham, Birmingham, AL, presents the results of the MILESTONE trial (NCT04991103) evaluating the use of measurable residual disease (MRD) response-adapted deferral of autologous stem cell transplantation (autoSCT) in patients with newly diagnosed multiple myeloma (MM). The study demonstrated that real-time MRD testing post-induction could guide decisions about proceeding to autoSCT, potentially sparing 25% of patients from the associated toxicities without compromising outcomes. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.

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