In this video, Talha Munir, MD, Leeds Teaching Hospitals NHS Trust, Leeds, UK, shares findings from the Phase III UK NCRI FLAIR trial (ISRCTN01844152), which is comparing ibrutinib plus venetoclax (I+V) to fludarabine, cyclophosphamide and rituximab (FCR) in patients with previously untreated chronic lymphocytic leukemia (CLL). In this trial, I+V with measurable residual disease (MRD)-guided duration of treatment resulted in an improvement in both progression-free survival and overall survival (PFS; OS) in this patient population. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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