Jeffrey Lancet, MD, of Moffitt Cancer Center, Tampa, FL, gives an overview of the importance of induction chemotherapy in the treatment of acute myeloid leukemia (AML). Whilst induction chemotherapy remains the standard of care in most patients with AML, older patients may benefit more from hypomethylating agents as primary treatment. Dr Lancet also discusses the therapeutic use of CPX-351, a liposomal formulation of cytarabine and daunorubicin, as a bridge to curative transplant. This interview took place during the ninth annual meeting of the Society of Hematologic Oncology (SOHO 2021) congress.