Arnon Nagler, MD, Sheba Medical Center, Tel-Aviv, Israel, discusses the exciting field of CAR T-cell therapy in acute myeloid leukemia (AML). Although the success of CAR T-cell therapy in other fields has not been translated into treatment for AML, Prof. Nagler reveals that research is progressing and in the future CAR T-cells for AML might be a possible treatment. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).