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ASH 2024 | Phase II IMpress study: imetelstat in patients with advanced MDS or AML failing HMA-based therapy
In this video, Uwe Platzbecker, MD, University of Leipzig, Leipzig, Germany, comments on the interim analysis results of the Phase II IMpress study (NCT05583552) evaluating the efficacy and safety of imetelstat in patients with advanced myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) failing hypomethylating agent (HMA)-based therapy. The study did not identify any new safety signals, but unfortunately, no remissions were achieved according to protocol-defined endpoints. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Amgen: Consultancy, Research Funding; BMS: Consultancy, Membership on an entity’s Board of Directors or advisory committees, Other: Travel support, Research Funding; MDS Foundation: Membership on an entity’s Board of Directors or advisory committees; Abbvie: Consultancy, Research Funding; Curis: Consultancy, Honoraria, Research Funding; Geron: Consultancy; Janssen: Consultancy, Honoraria, Research Funding; Merck: Research Funding; Novartis: Consultancy, Research Funding.
