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MPN Workshop of the Carolinas 2024 | Prefibrotic myelofibrosis: considerations for diagnosing and managing this entity

Prithviraj Bose, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the differences between prefibrotic myelofibrosis (MF), essential thrombocythemia (ET) and overt primary myelofibrosis (overt PMF), and highlights the distinguishable characteristics clinicians should use to diagnose these diseases. Dr Bose also highlights approaches to managing these diseases and further emphasizes the value of early intervention, with agents such as ruxolitinib and interferon, to delay disease progression. This interview took place at the 1st Annual MPN Workshop of the Carolinas in Asheville, NC.

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Disclosures

Research support: Incyte, BMS, CTI (Sobi), Morphosys, Karyopharm, Sumitomo, Ajax, Disc, Ionis, Geron, Janssen, Cogent, Blueprint, Kartos, Telios.; Honoraria/consulting fees: Incyte, BMS, CTI (Sobi), GSK, Abbvie, Morphosys, Pharma Essentia, Sumitomo, Karyopharm, Ionis, Disc, Geron, Morphic, Jubilant, Ono, Novartis, Blueprint, Cogent.