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Improving prognostication in CMML: the role of iCPSS

Luca Lanino, MD, Dana-Farber Cancer Institute, Boston, MA, discusses advances in prognostic risk stratification for patients with chronic myelomonocytic leukemia (CMML). Dr Lanino highlights the international CMML Prognostic Scoring System (iCPSS), which integrates clinical and molecular features to improve risk prediction and inform treatment decisions, including the optimal timing of allogeneic stem cell transplantation. This presentation took place at the 4th International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS/iwMPN) 2026, held in Washington, DC.

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