Arnon Nagler, MD, Chaim Sheba Medical Center, Tel-Aviv, Israel, explores the updated classification of acute myeloid leukemia (AML) with myelodysplastic (MDS)-related features according to the 2022 World Health Organization (WHO) and International Consensus Classification (ICC) guidelines. The classification categorizes patients into three groups based on TP53 nature. Those with complex karyotypes show poorer outcomes after allogeneic stem cell transplantation (alloSCT), while those with gene mutations exhibit more favorable outcomes. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.
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