Jean-Jacques Kiladjian, MD, PhD, Saint-Louis Hospital & Paris Diderot University, Paris, France, shares some updates on the role of ropeginterferon alfa-2b in the treatment of myeloproliferative neoplasms (MPNs), highlighting the efficacy of this agent in comparison to best available therapy (BAT). Prof. Kiladjian further discusses some results from a six-year follow-up study comparing the use of ropeginterferon versus BAT. This interview took place at the third annual Texas MPN Workshop (TMW) 2022, held in San Antonio, TX.