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ASH 2023 | The feasibility of TKI treatment discontinuation in patients with Ph+ ALL

Sabina Chiaretti, MD, PhD, University of Rome, Rome, Italy, discusses the results of a retrospective real-world study evaluating the feasibility of tyrosine kinase inhibitor (TKI) treatment discontinuation in patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). Dr Chiaretti reports that of the fourteen patients who discontinued TKI treatment for various reasons, almost all are still experiencing treatment-free remission (TFR), indicating that a TFR is feasible in selected adult patients with Ph+ ALL. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Incyte: Membership on an entity’s Board of Directors or advisory committees; Abbvie: Membership on an entity’s Board of Directors or advisory committees; Gilead: Membership on an entity’s Board of Directors or advisory committees; Pfizer: Membership on an entity’s Board of Directors or advisory committees; Amgen: Membership on an entity’s Board of Directors or advisory committees.