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IMS 2023 | The future of ADCs in treating multiple myeloma

Rakesh Popat, BSc, MBBS, MRCP, FRCPath, PhD, University College London Hospitals, London, UK, discusses the emerging role of antibody-drug conjugates (ADCs) for multiple myeloma. Belantamab mafodotin (belamaf) remains the only ADC indicated for multiple myeloma and whilst it is currently only used as a monotherapy, findings from the Phase I/II DREAMM-6 trial (NCT03544281) demonstrated promising results in patients receiving bortezomib and dexamethasone with belamaf. The Phase III DREAMM-7 (NCT04246047) and DREAMM-8 (NCT04484623) trials will additionally assess belamaf with existing combination therapies. This interview took place at the 20th International Myeloma Society (IMS) Annual Meeting, held in Athens, Greece.

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