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COMy 2025 | Organs or tissues frequently affected by extramedullary disease in patients with myeloma
In this video, Saurabh Zanwar, MD, MBBS, Mayo Clinic, Rochester, MN, briefly discusses which tissues are affected by extramedullary disease (EMD) in multiple myeloma. Dr Zanwar highlights that EMD can affect any organ system, and approximately 50% of patients experience visceral involvement. This interview took place at the 11th World Congress on Controversies in Multiple Myeloma (COMy) congress in Paris, France.
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Transcript
Yeah, there is no peculiar distinction in terms of tissues that are involved by extramedullary disease. It can involve pretty much any organ system, including anything head to toe really. So central nervous system, liver, pancreas, soft tissue, lymph node. What we have noted in the past is about 50% of patients have a visceral involvement, whereas the rest of the half have soft tissue or skin involvement...
Yeah, there is no peculiar distinction in terms of tissues that are involved by extramedullary disease. It can involve pretty much any organ system, including anything head to toe really. So central nervous system, liver, pancreas, soft tissue, lymph node. What we have noted in the past is about 50% of patients have a visceral involvement, whereas the rest of the half have soft tissue or skin involvement. There is some data to suggest that visceral extramedullary disease might have a worse outcome compared to soft tissue or lymph node extramedullary sites, but there is more granularity in that data to dig through.
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