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ICML 2023 | Bispecific antibodies in NHL: current insights and ongoing studies

Umberto Vitolo, MD, Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy, discusses the use of the bispecific antibodies glofitamab, epcoritamab and odronextamab in non-Hodgkin lymphoma (HL), focusing on diffuse large B-cell lymphoma (DLBCL). Glofitamab and epcoritamab have shown promising results in third-line and beyond, and even after transplantation or CAR-T. Prof. Vitolo also comments on the good safety profiles of glofitamab and epcoritamab, before describing combination therapies which are being investigated using these agents, such as glofitamab and polatuzumab vedotin. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.

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