ICML 2023 | Can A+AVD replace PET-directed strategies for the frontline treatment of Hodgkin lymphoma?
Stephen Ansell, MD, PhD, Mayo Clinic, Rochester, MI, discusses a debate on whether a combination of brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine chemotherapy (A+AVD) should replace PET-directed therapy for the frontline treatment of Hodgkin Lymphoma (HL). PET-directed strategies are beneficial when using intensive chemotherapy to reduce the risk of long-term toxicities. Prof. Ansell explains that novel combinations such as A+AVD are less toxic, allowing them to be utilized for a longer period of time and improve patient outcomes without the need for PET-directed strategies. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.
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